22 December 2016. Following our important publication on genetic and gene regulatory mechanisms by which some morbidly obese adults may remain healthy in the International PLoS One journal, Prof Haja Kadarmideen has been interviewed by the University of Copenhagen (UCPH) and all major newspapers around the world.
See original press release from UCPH here, main Danish newspaper Berlingske Tidlerne BT here and Videnskab.dk here, Scandinavian country’s newspaper here as well as from UK’s The Guardian Newspaper here and India’s Hindustan Times here
Other worldwide coverage are here: genomeweb, Vision Express, Yahoo India, Newsdog, Onmedica, Webindia, Infloria
and manymore newsblogs
We published an article in journal Nature on 28 Sept 2016 – a result of massive international collaboration across 160 international researchers from 17 countries, supported by more than 120 research funders.
Our paper reveals genes / genetic variants that are important link between an individual’s early childhood growth and their chances of developing life style diseases such as type 2 diabetes or cardio-metabolic problems in later life. These results highlight new approaches to treatment and prevention. It brings us much closer to personalized and predictive medicine, signifying the societal impact of these findings.
The original paper : “Genome-wide associations for birth weight and correlations with adult disease”, published in Nature can be seen here:
from videnskab.dk appears here:
There is now world-wide coverage of these findings in newspapers, magazines and internet sites.
It is my privilege to lead the BioChild Consortium (www.biochild.ku.dk) in Denmark that has substantially contributed to this research
International Symposium on Modern Cattle Breeding: Genomic Selection and Screening of Invitro Produced Embryos (MoCaS)
Venue: Fest Auditorium, Bülowsvej 17, Frederiksberg Campus, University of Copenhagen
Date: 6 September 2016
Time: 8:30 until 16:00
This one-day symposium brings together researchers, private companies and government agencies involved in modern cattle breeding employing combined use of genomics and invitro embryo production and in addressing animal welfare concerns around the use of invitro embryo technologies. The symposium presents the results from bi-lateral Danish-Brazilian GIFT (Genomic Improvement of Fertilization Traits in Cattle) consortium (www.gift.ku.dk) focused on this subject and invited talks from reputed speakers representing universities, private companies and government institutions. The symposium is open to the public.
REGISTER FOR THE SYMPOSIUM HERE
Symposium Chair and Moderator:
Haja Kadarmideen DVM, MVSc., PhD
Professor & Head – Animal Breeding, Quantitative Genetics and Systems Biology,
Department of Large Animal Sciences, Faculty of Health & Medical Sciences,
University of Copenhagen, Denmark
Contact: hajak_at_sund_dot_ku_dot_dk ; Tel: +45 23839890
Deadline for registration: 31 August 2016
Click HERE for the program of the day
We have an open PhD position. To read the complete project description, eligibility, responsibilities and to apply, please click on the web link below and follow the guidelines: http://jobportal.ku.dk/phd/?show=809088
The FeedOMICS project is an acronym for the project entitled: Systems Genomics, Transcriptomics and Metabolomics approaches for simultaneous improvement of feed efficiency and production in Danish pigs).
Professor Haja Kadarmideen received 6.5 million Danish kroner from The Danish Council for Independent Research – Technology and Production Sciences (DFF-FTP)
Professor Haja Kadarmideen received 6.5 million Danish Kroner from The Danish Council for Independent Research – Technology and Production Sciences (DFF-FTP) for his research project with an additional 2 million Danish kroner co-financed (total grant of ~ 8.5 million Danish Kroner).
Project Title: FeedOMICS: Systems Genomics, Transcriptomics and Metabolomics approaches for simultaneous improvement of feed efficiency and production in Danish pigs
Improvement of feed efficiency (FE) is one of the most important goals in pig production. However, any improvement in FE should not compromise production hence a balanced genetic selection is necessary. Multi-omics experiments including genomics and systematic integration of –omics data and modelling (systems biology) is a very promising approach to detect causal genetic and regulatory mechanisms underlying FE. The main aims of the FeedOMICS project are to investigate if genomic, transcriptomic and metabolomic profiles are different in genetically efficient and inefficient pigs for feed utilization in a systems biology experiment. If they are different, then genetics, bio- and metabolite- markers for FE will be identified and project will provide a deeper understanding of systems genetics and biological mechanisms of FE. The project will evaluate impact of these FE markers on production traits and eventually lead to testable genetic-, bio- and metabolite- markers for FE in blood & tissues. Application of systems genomic selection in the pig industry setting will be investigated.
Main Principal Investigator: Prof. Haja Kadarmideen, Head of Animal Breeding, Quantitative Genetics and Systems Genetics Group, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Co-Principal Investigator: Prof. Claus Thorn Ekstrøm, Head of Biostatistics Group, Dept. Public Health, SUND
Start – End Date: April 2016 – April 2019
Professor Haja Kadarmideen, Leader of the Animal Breeding, Quantitative Genetics and Systems Biology group at IKVH-SUND is a research partner representing the University of Copenhagen in a tri-national collaborative project on “Genomics applied to Ruminant Production”. The project has been granted approximately US$ 800,000 (DKK 5.26 million) by the São Paulo State Foundation (FAPESP) and the main principal investigator is Professor José Bento Sterman Ferraz from the University of São Paulo. Research partners are: College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), College of Agriculture and Veterinary Sciences, State University of Sao Paulo (FCAV/UNESP), School of Agronomy, University of São Paulo (ESALQ/USP), University of California, Davis, USA, and the Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Brief project description:
The Brazilian beef cattle, predominantly originating from Bos indicus breeds, have great importance in the world meat market, because the country has one of the largest beef herds in the world, with around 200 million head. The Nellore cattle breed (see inserted picture) comprises approximately 90% of the cattle population in Brazil. The sheep industry in Brazil has a herd of about 17.6 million head, but gets less attention than cattle production. Because of the importance of these animals for food consumption and economic growth, improvements are needed for efficient production, especially in the selection of genetically superior animals and animals that are resistant to adverse environments of the tropics. With increased demand for food worldwide, the quantity and quality of the production of animal protein is an important target of research. With recent advances in biotechnology, the use of high-density SNPchip allows us to develop strategies to identify genes or genomic regions responsible for traits of interest, making the selection process faster and more efficient. GWAS (Genome-Wide Association Study) identifies associations of genomic markers, or genomic regions with the important production phenotypes and resistance to diseases. The objective of this molecular-quantitative genetic project is to conduct GWAS, linkage disequilibrium analyses, detection of Copy Number Variations (CNVs) and functional enrichment in measures of growth, reproduction, meat quality and feed efficiency in Nellore cattle. Additionally, we will conduct global gene expression profiling (sequencing of total messenger RNA by RNASeq) and study epigenetic mechanisms that control the feed efficiency traits in Nellore cattle. The project will also address resistance to endoparasites and prolificacy in Santa Ines sheep.
Professor Haja Kadarmideen’s projects on pig production and human eating behaviour appears in the University of Copenhagen Christmas Calendar 2014. Click here for the news release
Associate Editor of Frontiers in Veterinary Science Journal (Livestock Genomics Section)