Project Title: FeedOMICS: Systems Genomics, Transcriptomics and Metabolomics approaches for simultaneous improvement of feed efficiency and production in Danish pigs
Improvement of feed efficiency (FE) is one of the most important goals in pig production. However, any improvement in FE should not compromise production hence a balanced genetic selection is necessary. Multi-omics experiments including genomics and systematic integration of –omics data and modelling (systems biology) is a very promising approach to detect causal genetic and regulatory mechanisms underlying FE. The main aims of the FeedOMICS project are to investigate if genomic, transcriptomic and metabolomic profiles are different in genetically efficient and inefficient pigs for feed utilization in a systems biology experiment. If they are different, then genetics, bio- and metabolite- markers for FE will be identified and project will provide a deeper understanding of systems genetics and biological mechanisms of FE. The project will evaluate impact of these FE markers on production traits and eventually lead to testable genetic-, bio- and metabolite- markers for FE in blood & tissues. Application of systems genomic selection in the pig industry setting will be investigated.
Main Principal Investigator: Prof. Haja Kadarmideen, Head of Animal Breeding, Quantitative Genetics and Systems Genetics Group, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Co-Principal Investigator: Prof. Claus Thorn Ekstrøm, Head of Biostatistics Group, Dept. Public Health, SUND
Start – End Date: April 2016 – April 2019